Journal of Orthopaedic Research

The Journal of Orthopaedic Research (JOR) is the premier source for advanced orthopaedic research in the world today. Fully searchable, the JOR research articles on musculoskeletal subjects range from microbiology to engineering to clinical work, and the archive is searchable all the way back to 1983. Members may also submit research articles of interest to the JOR editors for consideration in future publications.

To review the current journal and archives, to submit an article or to inquire about advertising, visit the search page at Wiley’s Online Library.

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Proceedings of the International Consensus Meeting on Periprosthetic Joint Infection







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Recently Published Articles

Journal of Orthopaedic Research

Wiley Online Library : Journal of Orthopaedic Research

Some patients do not have an adequate clinical response to total hip arthroplasty (THA) for reasons that are not fully understood. Identifying modifiable factors that are associated with nonresponse could lead to new ways to identify and treat potential nonresponders. This study investigated whet…
Author: Kharma C. Foucher
Posted: May 4, 2016, 11:00 pm
Facet joint osteoarthritis may be a cause of low back pain in degenerative spine diseases including lumbar spinal stenosis. Subchondral bone is regarded as a potential therapeutic target for osteoarthritis treatment. The goal of this study was to characterize subchondral bone histopathology in os…
Author: Cordula Netzer, Karin Urech, Thomas Hügle, Robyn Melanie Benz, Jeroen Geurts, Stefan Schären
Posted: May 4, 2016, 11:00 pm
Obesity is a well-known risk factor for osteoarthritis, but it is unknown what it does on cartilage repair. Here we investigated whether a high fat diet (HFD) influences cartilage repair in a mouse model of cartilage repair. We fed DBA/1 mice control or HFD (60% energy from fat). After two weeks,…
Author: Wu Wei, Yvonne M. Bastiaansen-Jenniskens, Mathijs Suijkerbuijk, Nicole Kops, Pieter K. Bos, Jan A.N. Verhaar, Anne-Marie Zuurmond, Francesco Dell’Accio, Gerjo J.V.M. van Osch
Posted: May 4, 2016, 10:55 pm
There is growing evidence in support of the involvement of inflammatory response in the pathogenesis of osteoarthritis (OA). Harpagoside, one of the bioactive components of Harpagophytum procumbens (Hp), has been shown to possess anti-inflammatory properties. Here we used an in vitro model of inf…
Author: Abdul Haseeb, Mohammad Yunus Ansari, Tariq M. Haqqi
Posted: May 4, 2016, 5:36 am
This study quantified the contributions by muscles, gravity, and inertia to the tibiofemoral compartment forces in the symptomatic (SYM) and asymptomatic (ASYM) limbs of varus mal-aligned medial knee osteoarthritis (OA) patients, and compared the results with healthy controls (CON). Muscle forces…
Author: Prasanna Sritharan, Yi-Chung Lin, Sara E. Richardson, Kay M. Crossley, Trevor B. Birmingham, Marcus G. Pandy
Posted: May 4, 2016, 5:26 am
Unicompartmental knee arthroplasty (UKA) is an effective surgical technique for pain relief and functional restoration in patients with localized osteoarthritis of the knee joint. However, the role of the joint line in UKA, especially its biomechanical effect, has not been previously investigated…
Author: Oh-Ryong Kwon, Kyoung-Tak Kang, Juhyun Son, Dong-Suk Suh, Changhyun Baek, Yong-Gon Koh
Posted: May 2, 2016, 9:52 pm
The post-surgery integrity of the tendons and muscle quality are the two major factors in success of rotator cuff (RC) repair. Though surgical techniques for rotator cuff repair have significantly improved in the past two decades, there are no effective treatments to improve tendon-to-bone healin…
Author: Mengyao Liu, Carlin Lee, Dominique Laron, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Brian Feeley, Xuhui Liu
Posted: May 2, 2016, 6:23 pm
In this multi-center study, voxel-based relaxometry (VBR), a novel technique to automatically quantify localized cartilage change, was used to investigate T1ρ and T2 relaxation times of patients with anterior cruciate ligament (ACL) tears at the time of injury and 6 months after reconstructive su…
Author: Colin Russell, Valentina Pedoia, Keiko Amano, Hollis Potter, Sharmila Majumdar,
Posted: May 2, 2016, 6:22 pm
Concentrations of pro- and anti-inflammatory cytokines in synovial fluid samples collected from patients with chronic meniscal tears were investigated. An acute inflammatory response is generally reported 24–48 h after knee injury, but the largest body of data available in literature concerns ant…
Author: Marco Bigoni, Marco Turati, Paola Sacerdote, Diego Gaddi, Massimiliano Piatti, Alberto Castelnuovo, Silvia Franchi, Marta Gandolla, Alessandra Pedrocchi, Robert J. Omeljaniuk, Elena Bresciani, Vittorio Locatelli, Antonio Torsello
Posted: May 2, 2016, 6:27 am
The objective of this study was to compare longitudinal results from two models of combined anterior cruciate ligament (ACL) and meniscal injury. A modified ACL transection (mACLT) model and a traumatic impact (ACLF) model were used to create an ACL rupture and acute meniscal damage in a Flemish …
Author: Kristine M. Fischenich, Keith D. Button, Charlie DeCamp, Roger C. Haut, Tammy L. Haut Donahue
Posted: April 29, 2016, 7:20 pm
Posted: April 29, 2016, 12:11 pm
Posted: April 29, 2016, 12:11 pm
Diffuse idiopathic skeletal hyperostosis (DISH) is a predominantly radiographic diagnosis and histological knowledge of DISH is limited. The aim of this study was to describe the histological characteristics of DISH in the spinal column and to study the relation between DISH and intervertebral di…
Author: Jonneke S. Kuperus, L. Anneloes Westerveld, Joost P. H. J. Rutges, Jacqueline Alblas, Mattie H. P. van Rijen, Ronald L. A. W. Bleys, F. Cumhur Öner, Jorrit-Jan Verlaan
Posted: April 29, 2016, 6:31 am
To determine the effect of high molecular weight hyaluronic acid (HA) on matrix metalloproteinase 13 (MMP13) expression induced by tumor necrosis factor α (TNF-α) in chondrocytes. Human chondrocytic C28/I2 cells were incubated with TNF-α and HA. In some experiments, the cells were pre-incubated w…
Author: Junya Furuta, Wataru Ariyoshi, Toshinori Okinaga, Jun Takeuchi, Sho Mitsugi, Kazuhiro Tominaga, Tatsuji Nishihara
Posted: April 29, 2016, 6:30 am
The objective of the study was to evaluate differences in gait mechanics 5 years after unilateral anterior cruciate ligament reconstruction surgery, for non-osteoarthritic (n = 24) versus osteoarthritic (n = 9) subjects. For the involved knee, the osteoarthritic group demonstrated significantly l…
Author: Ashutosh Khandha, Kurt Manal, Elizabeth Wellsandt, Jacob Capin, Lynn Snyder-Mackler, Thomas S. Buchanan
Posted: April 27, 2016, 5:25 am