Journal of Orthopaedic Research

The Journal of Orthopaedic Research (JOR) is the premier source for advanced orthopaedic research in the world today. Fully searchable, the JOR research articles on musculoskeletal subjects range from microbiology to engineering to clinical work, and the archive is searchable all the way back to 1983. Members may also submit research articles of interest to the JOR editors for consideration in future publications.

To review the current journal and archives, to submit an article or to inquire about advertising, visit the search page at Wiley’s Online Library.

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Proceedings of the International Consensus Meeting on Periprosthetic Joint Infection







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Recently Published Articles

Journal of Orthopaedic Research

Wiley Online Library : Journal of Orthopaedic Research

Post-traumatic joint stiffness (PTJS) of the elbow is a debilitating condition that poses unique treatment challenges. While previous research has implicated capsular tissue in PTJS, much regarding the development and progression of this condition remains unknown. The objective of this study was …
Author: Spencer P. Lake, Ryan M. Castile, Stephanie Borinsky, Chelsey L. Dunham, Necat Havlioglu, Leesa M. Galatz
Posted: July 31, 2015, 8:52 am
The purpose of the study was to test a novel treatment that carbodiimide-derivatized-hyaluronic acid-lubricin (cd-HA-lubricin) combined cell-based therapy in an immobilized flexor tendon repair in a canine model. Seventy-eight flexor tendons from 39 dogs were transected. One tendon was treated wi…
Author: Chunfeng Zhao, Yasuhiro Ozasa, Haruhiko Shimura, Ramona L. Reisdorf, Andrew R. Thoreson, Gregory Jay, Steven L. Moran, Kai-Nan An, Peter C. Amadio
Posted: July 31, 2015, 8:51 am
Early secure fixation of total joint replacements is crucial for long-term survival. Antiresorptive agents such as bisphosphonates have been shown to increase implant fixation. We investigated whether local delivery of zoledronate from poly-D, L-lactide (PDLLA)-coated implants could improve impla…
Author: Thomas Jakobsen, Joan E. Bechtold, Kjeld Søballe, Thomas Jensen, Stefan Greiner, Marianne T. Vestermark, Jørgen Baas
Posted: July 31, 2015, 8:23 am
Distraction osteogenesis (DO) is used to form new bone between bone segments to lengthen the callus. Skeletal muscles frequently fail to adapt to distraction, which causes complications. Insulin-like growth factor-1 (IGF-1) has been implicated as a central regulator of muscle repair. We hypothesi…
Author: Rui Feng, Xinlong Ma, Jianxiong Ma, Haobo Jia, Baoyi Ma, Liyan Xu, Aifeng Liu
Posted: July 31, 2015, 8:22 am
This study assessed the effects of static loading on MRI relaxation times of menisci in individuals with and without radiographic knee OA. High-resolution fast spin-echo (FSE) and T1ρ/T2 relaxation time MR sequences were obtained with and without loading at 50% body weight in 124 subjects. T1ρ/T2…
Author: Nathaniel E. Calixto, Deepak Kumar, Karupppasamy Subburaj, Justin Singh, Joseph Schooler, Lorenzo Nardo, Xiaojuan Li, Richard B. Souza, Thomas M. Link, Sharmila Majumdar
Posted: July 30, 2015, 10:14 am
Post-laminectomy/laminotomy epidural fibrosis (EF) has been implicated as an important cause of failed back syndrome (FBS). The various clinical approaches used to control EF yield mixed outcomes. Cross-linked hyaluronic acid hydrogel (cHA) was synthesized to increase mechanical stability and res…
Author: Cheng-Yi Wu, Yi-Hung Huang, Jung-Shun Lee, Ta-Wei Tai, Po-Ting Wu, I-Ming Jou
Posted: July 29, 2015, 2:25 pm
Low serum albumin levels and impaired kidney function have been associated with decreased survival in patients with a variety of cancer types.

In a retrospective cohort study, we analyzed 84 patients with liposarcoma treated at from May 1994 to October 2011. Uni- and multivariab…

Author: Joannis Panotopoulos, Florian Posch, Philipp T. Funovics, Madeleine Willegger, Anke Scharrer, Wolfgang Lamm, Thomas Brodowicz, Reinhard Windhager, Cihan Ay
Posted: July 29, 2015, 2:24 pm
Osteoporosis and osteoarthritis commonly coexist in the elderly. In patients undergoing prosthetic total knee arthroplasty (TKA), the bone quality around the knee joint may affect the safety of prosthetic implantation and consequently satisfaction with the surgical outcome. We recruited 50 postme…
Author: Chuan-Ching Huang, Ching-Chuan Jiang, Chang-Hsun Hsieh, Chia-Jung Tsai, Hongsen Chiang
Posted: July 29, 2015, 2:24 pm
Episodes of care defined by the event of hip fracture surgery are widely used for the assessment of surgical wait times and outcomes. However, this approach does not consider nonoperative deaths, implying that survival time begins at the time of procedure. This approach makes treatment effect imp…
Author: Katie Jane Sheehan, Boris Sobolev, Pierre Guy, Eric Bohm, Erik Hellsten, Jason M. Sutherland, Lisa Kuramoto, Susan Jaglal,
Posted: July 29, 2015, 1:28 pm
Osteoarthritis is a chronic degenerative disease that affects the articular cartilage. Recent studies have demonstrated that lithium chloride exhibits significant efficacy as a chondroprotective agent, blocking cartilage degradation in response to inflammatory cytokines. However, conflicting lite…
Author: Clare L. Thompson, Habiba Yasmin, Anna Varone, Anna Wiles, C. Antony Poole, Martin M. Knight
Posted: July 29, 2015, 8:59 am
Total joint replacement (TJR) has been widely used as a standard treatment for late-stage arthritis. One challenge for long-term efficacy of TJR is the generation of ultra-high molecular weight polyethylene wear particles from the implant surface that activates an inflammatory cascade which may l…
Author: Xinyi Jiang, Taishi Sato, Zhenyu Yao, Michael Keeney, Jukka Pajarinen, Tzu-hua Lin, Florence Loi, Kensuke Egashira, Stuart Goodman, Fan Yang
Posted: July 29, 2015, 8:59 am
The relationship between modern clinical diagnostic data, such as from radiographs or computed tomography, and the temporal biomechanical integrity of bone fracture healing has not been well-established. A diagnostic tool that could quantitatively describe the biomechanical stability of the fract…
Author: Kirk C. McGilvray, Emre Unal, Kevin L. Troyer, Brandon G. Santoni, Ross H. Palmer, Jeremiah T. Easley, Hilmi Volkan Demir, Christian M. Puttlitz
Posted: July 29, 2015, 8:58 am
Femoral neck fractures in the elderly are a common problem in orthopedics. Augmentation of screw fixation with bone cement can provide better stability of implants and lower the risk of secondary displacement. This study aimed to investigate whether cement augmentation of three cannulated screws …
Author: Ladina Hofmann-Fliri, Tomas I. Nicolino, Jorge Barla, Boyko Gueorguiev, R. Geoff Richards, Michael Blauth, Markus Windolf
Posted: July 29, 2015, 8:57 am
Patient-to-patient differences should be accounted for in both clinical evaluations and computational models of knee laxity. Accordingly, the objectives were to determine how variable the laxities are between knees by determining the range of the internal-external (I-E), varus-valgus (V-V), anter…
Author: Joshua D. Roth, Maury L. Hull, Stephen M. Howell
Posted: July 28, 2015, 12:53 pm
Methods are needed for identifying poorer quality cadaver proximal humeri to ensure that they are not disproportionately segregated into experimental groups for fracture studies. We hypothesized that measurements made from radiographs of cadaveric proximal humeri are stronger predictors of fractu…
Author: John G. Skedros, Alex N. Knight, Todd C. Pitts, Peter J. O’Rourke, Wayne Z. Burkhead
Posted: July 27, 2015, 10:46 am