Journal of Orthopaedic Research

The Journal of Orthopaedic Research (JOR) is the premier source for advanced orthopaedic research in the world today. Fully searchable, the JOR research articles on musculoskeletal subjects range from microbiology to engineering to clinical work, and the archive is searchable all the way back to 1983. Members may also submit research articles of interest to the JOR editors for consideration in future publications.

To review the current journal and archives, to submit an article or to inquire about advertising, visit the search page at Wiley’s Online Library.

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Proceedings of the International Consensus Meeting on Periprosthetic Joint Infection

 

 

 

 

 

 

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Recently Published Articles

Journal of Orthopaedic Research

Wiley Online Library : Journal of Orthopaedic Research

Degeneration of the intervertebral discs is strongly implicated as a cause of low back pain. Since current treatments for discogenic low back pain show poor long-term efficacy, a number of new, biological strategies are being pursued. For such therapies to succeed, it is critical that they be val…
Author: Deborah J Gorth, Katherine E Lothstein, Joseph A Chiaro, Megan J Farrell, George R Dodge, Dawn M Elliott, Neil R Malhotra, Robert L Mauck, Lachlan J Smith
Posted: January 30, 2015, 9:23 pm
Purpose
The aim of this study was to investigate interactions between variants within genes encoding components of the collagen fibril and components of cell-signalling pathways within the extracellular matrix, anddetermine the relative contribution of these variants to Achilles tendinopathy risk…
Author: Colleen J. Saunders, Lize van der Merwe, Jill Cook, Christopher J. Handley, Malcolm Collins, Alison V. September
Posted: January 30, 2015, 9:22 pm
This study compared fracture repair stabilized by intramedullary pin (IMP) or external fixation (EF) in GFP reporter mice. A modified IMP was used as control while EF utilized 6 needles inserted transversely through the tibia and into a segment of a syringe barrel. X-rays taken at day 0, 14 and 3…
Author: Y. Hagiwara, N.A. Dyment, X. Jiang, J. Huang, C. Ackert-Bicknell, D.J. Adams, D.W. Rowe
Posted: January 30, 2015, 9:22 pm
Osteoarthritis is a leading cause of human suffering and disability for which disease modifying treatments are lacking. OA occurs through complex and dynamic interplays between diverse factors over long periods of time. The traditional research and clinical focus on OA, the end stage disease,obsc…
Author: Constance R. Chu, Thomas P. Andriacchi
Posted: January 30, 2015, 9:22 pm
Chordomas mainly arise along the axial skeleton and are characterized by their slow but destructive growth. Prognosis and quality of life are poor because treatment options are mainly limited to surgery and radiotherapy. Survivin, a member of the apoptosis inhibitor protein family, functions as a…
Author: Elke V. Froehlich, Beate Rinner, Alexander J.A. Deutsch, Katharina Meditz, Heike Knausz, Katharina Troppan, Susanne Scheipl, Christine Wibmer, Andreas Leithner, Bernadette Liegl, Birgit Lohberger
Posted: January 30, 2015, 9:21 pm
This article is one of a series, summarising views expressed at the Orthopaedic Research Society New Frontiers in Tendon Research Conference. This particular article reviews the three workshops held under the “Functional Extracellular Matrix” stream. The workshops focused on the roles of the tend…
Author: H.R.C. Screen, D.E. Birk, K.E. Kadler, F. Ramirez, M.F. Young
Posted: January 30, 2015, 9:21 pm
The use of interactive surgical scenarios for virtual preoperative planning of osteotomies has increased in the last 5 years. As it has been reported by several authors, this technology has been used in tumor resection osteotomies, knee osteotomies and spine surgery with good results. A digital t…
Author: Federico Edgardo Milano, Lucas Eduardo Ritacco, Germán Luis Farfalli, Luis Alberto Bahamonde, Luis Alberto Aponte-Tinao, Marcelo Risk
Posted: January 30, 2015, 9:06 pm
Purpose
Long bone defectscan be managed by the induced membrane technique together withautologous bone graft. However,graft harvestis associated with donor site morbidity. This study investigates if a tricalcium phosphate hydroxyapatite scaffold can be used alone or in combination with bone activ…
Author: Per Bosemark, Christina Perdikouri, Mea Pelkonen, Hanna Isaksson, Magnus Tägil
Posted: January 30, 2015, 9:06 pm
Local anesthetics (LA) are among the drugs most frequently used for musculoskeletal problems, in procedures ranging from diagnosis to postoperative pain control. The cytotoxicity of LA is an emerging area of concern. The purpose of this study was to determine whether cyanidin, an antioxidant, exe…
Author: Ra Jeong Kim, Young-Sool Hah, Jae-Ran Kang, Hyung Bin Park
Posted: January 30, 2015, 9:06 pm
Linear growth failure results from a broad spectrum of systemic and local disorders that can generate chronic musculoskeletal disability. Current bone lengthening protocols involve invasive surgeries or drug regimens, which are only partially effective. Exposure to warm ambient temperature during…
Author: Maria A. Serrat, Thomas J. Schlierf, Morgan L. Efaw, Franklin D. Shuler, Justin Godby, Laura M. Stanko, Holly L. Tamski
Posted: January 30, 2015, 9:05 pm
Introduction
Besides the use of autologous bone grafting several osteoconductive and osteoinductive methods have been reported to improve bone healing. However, persistent non-union occurs in a considerable number of cases and compromised angiogenesisis suspectedto impede bone regeneration. Hyper…
Author: JP Grassmann, J Schneppendahl, AR Hakimi, M Herten, M Betsch, TT Lögters, S Thelen, M Sager, M Wild, J Windolf, P Jungbluth, M Hakimi
Posted: January 29, 2015, 9:41 pm
To date, there have been few studies on how temperature affects the phenotype and metabolism of human chondrocytes. Thus, the purpose of this study was to elucidate the effects of culture temperature on chondrocyte redifferentiation and extracellular matrix (ECM) formation using dedifferentiated …
Author: Akira Ito, Tomoki Aoyama, Hirotaka Iijima, Junichi Tajino, Momoko Nagai, Shoki Yamaguchi, Xiangkai Zhang, Hiroshi Kuroki
Posted: January 29, 2015, 9:41 pm
To observe the effects of LIM mineralization protein-1 (LMP-1) on bone regeneration in the distraction zone based on gene transduction, 36 New Zealand white rabbits underwent mandibular lengthening with a distraction rate of 2 mm/day. The animals were then randomly divided into group A and group …
Author: Xiaowen Jiang, Yanzhe Chen, Xiaosheng Fan, Hao Zhang, Kun Lu
Posted: January 29, 2015, 9:41 pm
Tendon disorders are common and lead to significant disability, pain, healthcare cost, and lost productivity. A wide range of injury mechanisms exist leading to tendinopathy or tendon rupture. Tears can occur in healthy tendons that are acutely overloaded (e.g., during a high speed or high impact…
Author: Stavros Thomopoulos, William C. Parks, Daniel B. Rifkin, Kathleen A. Derwin
Posted: January 29, 2015, 9:41 pm
Purpose
This work evaluates the ability of MRIcontrasts to discriminate between normal and pathological human osteochondral plugscharacterized by the OARSI histological system.

Methods
Normal and osteoarthritic human osteochondralplugswere scored using the OARSI histological system and imaged a…

Author: Vanessa A. Lukas, Kenneth W. Fishbein, Ping-Chang Lin, Michael Schär, Erika Schneider, Corey P. Neu, Richard G. Spencer, David A. Reiter
Posted: January 29, 2015, 9:41 pm