Journal of Orthopaedic Research

Call for Papers for a Special Theme Issue of the Journal of Orthopaedic Research:  New Frontiers in Tendon Research


The Journal of Orthopaedic Research (JOR) is the premier source for advanced orthopaedic research in the world today. Fully searchable, the JOR research articles on musculoskeletal subjects range from microbiology to engineering to clinical work, and the archive is searchable all the way back to 1983. Members may also submit research articles of interest to the JOR editors for consideration in future publications.

To review the current journal and archives, to submit an article or to inquire about advertising, visit the search page at Wiley’s Online Library.

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Recently Published Articles

Journal of Orthopaedic Research

Wiley Online Library : Journal of Orthopaedic Research

Wear testing cannot replicate the variations in wear rates and wear mechanisms seen in vivo, which may be related to differences between in vivo and in vitro conditions. A considerable difference exists between the in vivo synovial fluid volume (few milliliter) and the in vitro substituted bovine…
Author: Jörn Reinders, Robert Sonntag, Jan Philippe Kretzer
Posted: September 22, 2014, 6:36 am
Microfracture repair tissue in young adult humans and in rabbit trochlea is frequently of higher quality than in corresponding ovine or horse models or in the rabbit medial femoral condyle (MFC). This may be related to differences in subchondral properties since repair is initiated from the bone….
Author: Anik Chevrier, Ahou S. M. Kouao, Genevieve Picard, Mark B. Hurtig, Michael D. Buschmann
Posted: September 19, 2014, 5:42 pm
Muscle contractures that occur after upper motor neuron lesion are often surgically released or lengthened. However, surgical manipulation of muscle length changes a muscle’s sarcomere length (Ls), which can affect force production. To predict effects of surgery, both macro- (fascicle length (Lf)…
Author: Margie A. Mathewson, Samuel R. Ward, Henry G. Chambers, Richard L. Lieber
Posted: September 19, 2014, 5:40 pm
Open fracture is a common occurrence in civilian and military populations. Though great strides have been made in limb salvage efforts, persistent muscle strength deficits can contribute to a diminished limb function after the bone has healed. Over the past decade, a growing effort to establish t…
Author: Koyal Garg, Catherine L. Ward, Brady J. Hurtgen, Jason M. Wilken, Daniel J. Stinner, Joseph C. Wenke, Johnny G. Owens, Benjamin T. Corona
Posted: September 18, 2014, 6:53 am
Supraspinatus (SS) tendon tears are common musculoskeletal injuries whose surgical repair exhibits the highest incidence of re-tear of any tendon. Development of therapeutics for improving SS tendon healing is impaired by the lack of a model that allows biological perturbations to identify mechan…
Author: Rebecca Bell, Peter Taub, Paul Cagle, Evan L. Flatow, Nelly Andarawis-Puri
Posted: September 18, 2014, 6:52 am
Consensus has not been reached regarding the ability of pathologic fracture to predict local recurrence and survival in osteosarcoma. We aim to review the available evidence to examine the association between pathologic fracture and osteosarcoma prognosis. A comprehensive literature search for re…
Author: Lingling Sun, Yingiun Li, Jian Zhang, Hengyuan Li, Binghao Li, Zhaoming Ye
Posted: September 18, 2014, 6:52 am
Family with sequence similarity 46, member A (FAM46A) gene VNTR and BCL2-Associated Athanogene 6 (BAG6) gene rs3117582 polymorphisms were genotyped in a case–control study with 474 large-joint (hip and knee) osteoarthritis (OA) patients and 568 controls in Croatian population by candidate-gene ap…
Author: Godfrey E. Etokebe, Zdravko Jotanovic, Radovan Mihelic, Biserka Mulac- Jericevic, Tamara Nikolic, Sanja Balen, Branko Sestan, Zlatko Dembic
Posted: September 18, 2014, 6:52 am
Variations in sacral segmentation may preclude safe placement of transsacral screws for posterior pelvis fixation. We developed a novel automated 3D technique to determine the safe zone size for transsacral screws in the upper two sacral segments in 526 adult pelvis computed tomography scans. Saf…
Author: John J. Lee, Samuel L. Rosenbaum, Alex Martusiewicz, Sven A. Holcombe, Stewart C. Wang, James A. Goulet
Posted: September 17, 2014, 3:43 pm
This study investigated the effects of local delivery of manganese chloride (MnCl2), an insulin-mimetic compound, upon fracture healing using a rat femoral fracture model. Mechanical testing, histomorphometry, and immunohistochemistry were performed to assess early and late parameters of fracture…
Author: Jeremy Hreha, Aaron Wey, Catherine Cunningham, Ethan S. Krell, Eric A. Brietbart, David N. Paglia, Nicholas J. Montemurro, Daniel A. Nguyen, Yung-Jae Lee, Daniel Komlos, Elisha Lim, Joseph Benevenia, J. Patrick O’Connor, Sheldon S. Lin
Posted: September 17, 2014, 3:43 pm
Activated Protein C (APC) is an anticoagulant with strong cytoprotective properties that has been shown to promote wound healing. In this study APC was investigated for its potential orthopedic application using a Bone Morphogenetic Protein 2 (rhBMP-2) induced ectopic bone formation model. Local …
Author: Kaitlin Shen, Ciara M. Murphy, Ben Chan, Mille Kolind, Tegan L. Cheng, Kathy Mikulec, Lauren Peacock, Meilang Xue, Sang-Youel Park, David G. Little, Chris J. Jackson, Aaron Schindeler
Posted: September 15, 2014, 3:00 pm
Glucosamine is an endogenous amino monosaccharide naturally occurring in the cartilage. We have recently shown that glucosamine sulfate promotes the biosynthesis of glycosaminoglycans in intervertebral disc cells. Here we assessed the role of glucosamine sulfate in the response of bovine nucleus …
Author: Eleni Mavrogonatou, Maria T. Angelopoulou, Dimitris Kletsas
Posted: September 12, 2014, 3:35 pm
Human fracture healing is a complex interaction of several cytokines that regulate osteoblast and osteoclast activity. By monitoring OPG (osteoprotegerin) and sRANKL we aimed to possibly predict normal or impaired fracture healing. In 64 patients with a fracture of a long bone serum level of sRAN…
Author: Julia Köttstorfer, Anita Thomas, Markus Gregori, Mathias Kecht, Georg Kaiser, Stefan Eipeldauer, Kambiz Sarahrudi
Posted: September 12, 2014, 8:07 am
The development of osteoarthritis (OA) depends on genetic and environmental factors, which influence the biology of the chondrocyte via epigenetic regulation. Changes within the epigenome might lead the way to discovery of new pathogenetic pathways. We performed a genome-wide methylation screenin…
Author: Florentine C. Moazedi-Fuerst, Manuela Hofner, Gerald Gruber, Andreas Weinhaeusel, Martin H. Stradner, Birgit Lohberger, Mathias Glehr, Andreas Leithner, Markus Sonntagbauer, Winfried B. Graninger
Posted: September 12, 2014, 8:06 am
Osteoarthritis (OA) is a group of common, chronic, and painful inflammatory joint diseases. One important finding in OA patients is a remarkable decrease in the molecular weight of hyaluronic acid (HA) in the synovial fluid of affected joints. Therapeutic HA is available to patients in most parts…
Author: Eiichi Sato, Takashi Ando, Jiro Ichikawa, Genki Okita, Nobutaka Sato, Masanori Wako, Tetsuro Ohba, Satoshi Ochiai, Tetsuo Hagino, Richard Jacobson, Hirotaka Haro
Posted: September 8, 2014, 8:04 am
The purpose of this study was to analyze histologic, biochemical, and biomechanical differences between zonal, regional, and anatomic locations of porcine menisci. We evaluated six menisci removed from pigs. Medial and lateral menisci were divided into three regions: anterior, middle, and posteri…
Author: Xiangkai Zhang, Tomoki Aoyama, Akira Ito, Junichi Tajino, Momoko Nagai, Shoki Yamaguchi, Hirotaka Iijima, Hiroshi Kuroki
Posted: September 7, 2014, 5:44 am