Techniques for Measuring Mechanical Properties of Tissue

Saturday, March 10
11:00 AM – 11:30 AM

Organized by: TA Instruments – ElectroForce Systems Group
Speaker: Luis Morales

The presentation will focus on techniques for mechanical characterization of: Orthopaedic Tissues, Vascular Tissues, Artificial Biomaterials, plus an overview of In Vivo Loading of Bone 

Objectives:

  • Orthopaedic Tissues material characterization
  • Vascular Tissues material characterization
  • Artificial Biomaterials material characterization

Bone Scaffold Characterizations and In Vivo Performance by Micro and Nano-CT

Saturday, March 10
5:00 PM – 5:30 PM

Organized by: Bruker BioSpin
Speakers:
Håvard Jostein Haugen, Head of the Department of Biomaterials, Institute for Clinical Dentistry, University of Oslo, Norway
Liebert Parreiras Nogueira, Department of Biomaterials, Institute for Clinical Dentistry, University of Oslo, Norway

Three-dimensional (3D) structures find applications in the biomedical field mainly as scaffolds for tissue engineering and regenerative medicine, as for most tissues (e. g., bone tissue, blood vessel, muscle tissue) a porous support guiding growing tissue is crucial. Their characterization appears to be fundamental, as the architectural parameters, porosity in particular, but also pore size, interconnectivity, strut size, shape and anisotropy, strongly affect the mechanical and biological performance of the 3D structures, and thus their functionality.

Micro-computed tomography is a powerful technique which allows the nondestructive characterization of such materials in a fast, automated and high accuracy way. We will present the most recent developments in scaffold and bone characterization by Micro and Nano-CT, developed at the Department of Biomaterials, Institute for Clinical Dentistry, University of Oslo, Norway.

Objectives:

  • Advanced characterization of bone graft substitute
  • Enhancement microCT evaluation of bone-titanium implants interphases
  • Microstructure characterization at nanoscale

How Mechanical Testing Can Enhance Your Research Studies

Sunday, March 11
4:45 PM – 5:15 PM

Organized by: Biomomentum Inc.
Speaker: Dr. Denis Evseenko

Mechanical testing is imperative in experimental studies as an outcome measure to assess and confirm the effects of numerous treatments on musculoskeletal tissues. Not only does mechanical testing offer direct and fast results – on the same day, it also evaluates the structure and function of the tissues. Due to the nature of musculoskeletal tissues – commonly anisotropic, porous, viscoelastic composite materials with diverse mechanical properties – Biomomentum has developed an important expertise and tools for mechanical testing procedures. We provide a broad range of testing capabilities including compression, tension, bending, torsion, friction, shear, 3D normal indentation, and novel mappings methods. This workshop will present different studies where mechanical testing has been added to the study protocol and helps prove the value of functional testing to obtain rapid and reliable outcomes.

Advanced Histomorphyometry of Musculoskeletal Systems

Monday, March 12
11:00 AM – 11:30 AM

Organized by: BIOQUANT Image Analysis Corporation
Speaker: Prof. Oran Kennedy, Royal College of Surgeons in Ireland

This workshop will present analytical methods for histology in various musculoskeletal systems, with a basis in digital pathology. Quantitative analysis of trabecular and cortical bone phenotypes, articular cartilage, dynamic responses of cortical bone, osteolytic tumor growth, and implant osseointegration will be considered. Additional comments will be shared on recent successes and remaining challenges in the automated analysis of skeletal muscle.

Objectives:

  • Document basic methods necessary to prepare and image histology for analysis by histomorphometry
  • Summarize analysis protocols for a variety of tissues in musculoskeletal systems
  • Share recent advances and remaining challenges in the analysis of skeletal muscle