Antonia F. Chen, MD, MBA, Brigham and Women’s Hospital
Noreen Hickok, PhD, Thomas Jefferson University
Amber Jennings, PhD, University of Memphis
Musculoskeletal infections are a common and a devastating complication in orthopaedics, particularly when implants are required to restore function. The challenge of preventing or eliminating infection in bone has been met with several new advances in therapeutic approaches and clinical practice; however, infection rates remain at an unacceptable level. This RIG will be a forum where clinicians, engineers, and biologists discuss the challenges and highlight new approaches and discoveries. The topic of infection will be broken into the 3B’s of orthopaedic infection: biofilm, bone, and biomaterials; the focus of this RIG 2021 meeting will be on understanding the interaction between biofilm-associated bacteria with immune and bone tissues, as well as opportunities for designing more effective biomaterial therapies for infection. We aim to continue building a dedicated infection research community presence during future ORS meetings.
Clinically Reliable Anti-infection Biomaterials for Bone Repair: Do they Exist?
New Biomaterials on the Horizon for Orthopaedic Infection
A Bug’s Eye View of Biofilm-associated Orthopaedic Infection
Staphylococcus Aureus Biofilm Promotes Leukocyte Dysfunction during Orthopaedic Infection
The Role of the Immune System in a Mouse Model of Periprosthetic Joint Infection
Hide and Seek: Are We Reaching Biofilm in Bone?