Research Interest Groups (RIG)
Organizers:
Rachel E. Miller, PhD, Rush University Medical Center
Tim M. Griffin, PhD, Oklahoma Medical Research Foundation
Interdisciplinary approaches are needed to address OA as a complex heterogeneous disease involving multiple organ systems and connective tissues. This complexity poses substantial challenges for developing new solutions to treat and prevent OA, which is now considered a serious disease. The goal of this program is to leverage the interdisciplinary strengths of ORS and OARSI to stimulate and propose new strategic scientific approaches and patient-centric recommendations that exist at the interface between disciplines to address OA. The discussion theme this year will focus on innovative approaches to study OA pain under an interdisciplinary format that integrates elements of inflammation, pain biology and mechanics. The presentations and discussion will focus on translation of research to clinically relevant patient-focused outcomes. Overall, we hope that this group will provide an opportunity for OA researchers to interact during this virtual meeting.
Relationship Between Inflammation and Pain in Osteoarthritis
Carla R. Scanzello, MD PhD, University of Pennsylvania
Translational Considerations – Preclinical Assessments of Pain
Tamara King, PhD, University of New England
In Vivo Imaging, Muscle Neuromechanics, and Rehabilitation for OA Prevention
Jason Franz, PhD, University of North Carolina at Chapel Hill
Support provided by:
Organizers:
Daniel Latt, MD, University of Arizona
William Ledoux, PhD, VA Puget Sound
Meade Spratley, PhD, University of Virginia
Bart Lubberts, MD, PhD, Massachusetts General Hospital
The foot and ankle is one of the newest and fastest growing areas of orthopaedic research. Relatively little is known about the foot in comparison to anatomic regions, such as the hip and knee, that have long been the subject of orthopaedic studies. Foundational (basic science) research in the foot and ankle will need to expand rapidly to keep pace with the clinical practice and applied research. The Foot and Ankle RIG will advance the science underpinning foot and ankle care by promoting communication and fostering collaborations among individuals interested in foot and ankle research. It’s goal is to serve as a network to facilitate the interaction between basic scientists, translational researchers, and clinicians interested in collaborating on foot and ankle orthopaedic science.
How our Understanding of 3D Kinematics of the Foot and Ankle Gained from Weight Bearing CT is Changing Clinical Practice and Research
Scott Ellis, MD, Hospital for Special Surgery
Assignment of Local Coordinate Systems and Methods to Calculate Tibiotalar and Subtalar Kinematics
Karen Kruger, PhD, Marquette University and Amy Lenz, PhD, University of Utah
Poster Teaser Presentations
Organizers:
Antonia F. Chen, MD, MBA, Brigham and Women’s Hospital
Noreen Hickok, PhD, Thomas Jefferson University
Amber Jennings, PhD, University of Memphis
Musculoskeletal infections are a common and a devastating complication in orthopaedics, particularly when implants are required to restore function. The challenge of preventing or eliminating infection in bone has been met with several new advances in therapeutic approaches and clinical practice; however, infection rates remain at an unacceptable level. This RIG will be a forum where clinicians, engineers, and biologists discuss the challenges and highlight new approaches and discoveries. The topic of infection will be broken into the 3B’s of orthopaedic infection: biofilm, bone, and biomaterials; the focus of this RIG 2021 meeting will be on understanding the interaction between biofilm-associated bacteria with immune and bone tissues, as well as opportunities for designing more effective biomaterial therapies for infection. We aim to continue building a dedicated infection research community presence during future ORS meetings.
Clinically Reliable Anti-infection Biomaterials for Bone Repair: Do they Exist?
David Grainger
New Biomaterials on the Horizon for Orthopaedic Infection
Bingyun Li
A Bug’s Eye View of Biofilm-associated Orthopaedic Infection
Mark Smeltzer
Staphylococcus Aureus Biofilm Promotes Leukocyte Dysfunction during Orthopaedic Infection
Tammy Kielian
The Role of the Immune System in a Mouse Model of Periprosthetic Joint Infection
Matthias Bostrom
Hide and Seek: Are We Reaching Biofilm in Bone?
Amber Jennings
Research Section Scientific Meetings
ORS Sections are smaller, intimate communities of like-minded peers that promote the common interest of ORS members in a specific area of research related to orthopaedics and the musculoskeletal system.
