Virtual participation is available for the sessions listed below.
After registration, participants will be provided with a ZOOM link allowing them access to the session. During the session, virtual participants will be able to view the PowerPoint presentations and hear the audio only. Any questions will need to be asked via the ZOOM chat feature. There will be no two-way communication with in-person participants. If the session includes round table discussions or breakouts virtual participants can choose to participate in the session amongst themselves.
Research Section Scientific Meetings
All Section Members and those who recently/newly JOINED a Section may attend the Virtual Section Meeting(s) at a discounted rate of $30. If you are not a Member of a Section, but the Section in which you have interest permits attendance by Non-Section Members, Non-Section Members may register at a rate of $60/each.
Section Members Only
Saturday, February 5, 2022
12:15 PM – 3:00 PM
The meeting will include:
Ice Breakers
Organized by: ORS Meniscus Section Communications & Networking Committee
ORS Meniscus Section Plenary: Deriving embryonic cells for the regeneration of dense connective tissues
Alice Huang, PhD, Columbia University
Moderators:
Matthew Koff, PhD, Hospital for Special Surgery
Jennifer Robinson, PhD (Membership Chair), University of Kansas
Poster Pitch Session
From invited ORS Meniscus Section members based on submitted abstracts to the ORS 2022 Annual Meeting. More information coming soon!
Moderators:
Alejandro Almarza, PhD, University of Pittsburgh
Salomi Desai, Brown University /Rhode Island Hospital
Podium Short Talks
Microstructural imaging of human meniscus ex vivo
Simo Saarakkala, PhD, University of Oulu, Finland
CRIPSR – Solutions for Fibrocartilage and Beyond
Robert Bowles, PhD, University of Utah
Bridge-Enhanced ACL Restoration: Taking a novel product from concept to clinic
Martha Murray, MD, Harvard Medical School
Moderators:
Marianne Black, PhD, Stanford University
Jay Patel, PhD, Emory University
With support provided by:
Inspiring Transformation in Impaired Fracture Healing Treatment
ISFR Members Only
3:00 PM – 6:00 PM Scientific Meeting
6:00 PM – 7:00 PM Networking
This scientific meeting focused on fracture non-union will present clinical aspects of non-union diagnosis and treatment, application of cutting edge technologies underutilized in orthopaedics, and research from our section’s emerging scientists. Recipients of our newly created Travel Exchange Grant and Life-Time Achievement Award will also present. A networking reception will immediately follow.
Section Members Only
Sunday, February 6, 2022
12:15 PM – 1:15 PM
Orthopaedic implants have been extremely successful in improving the quality of life for millions of patients. However, currently there are debates on what are the best clinical practices for implant alignment that will afford patients a best chance for optimal function and outcomes. This portion of our meeting will focus on clinical issues with implant support and alignment in total shoulder arthroplasty from a clinician’s viewpoint and a discussion on how the functional mechanics of the shoulder are best served by an academic engineer researcher. In total knee arthroplasty a discussion on newer alignment techniques and the theory behind kinematic alignment will be presented by a clinician and the issues with TKA joint modeling to determine the effects of implant design and alignment will be given by a corporate engineer.
Open to all Meeting Attendees
Sunday, February 6, 2022
1:30 PM – 3:00 PM
This portion of the meeting will be focused on Additive Manufacturing (AM) and will be a debate style format on whether AM has made a difference in clinical care. The pro side of the argument will be tackled by Hospital for Special Surgery by a clinician and an engineer researcher. The con side of the argument will be presented Rush University Medical Center by a clinician and an engineer researcher.
With support provided by:
Sunday, February 6, 2022
12:15 PM – 12:45 PM
This portion of the meeting will be for Section members only and a boxed lunch will be provided. Non-Section members will have the opportunity to join the ORS and/or ORS Section at the door.
Open to All Meeting Attendees,
1:00 PM – 3:00 PM
This portion of the meeting is open to ALL registered meeting attendees. However, admittance to the meeting will be based on availability (capacity of the room).
Section Members Only
Saturday, February 5, 2022
12:15 PM – 3:00 PM
We will hear unique perspectives from key stakeholders in basic science research and clinical medicine and hold panel and round table discussions to better understand current clinical challenges that basic scientists and engineers can work to address with significant clinical impact. The meeting promises to be a fun and interactive forum for trainees and established investigators to share ideas and debate the future of spine research.
The meeting will include:
Business Meeting
Poster Pitch Session
From invited ORS Spine Section Student and Post-Graduate Trainee members based on submitted abstracts to the ORS 2022 Annual Meeting. More information coming soon!
Moderators: TBA
Clarifying Cross-Talk With the Intervertebral Disc to Resolve Clinical Spine Problems
Raj Rampersaud, MD, University of Toronto
Jeannie Bailey, PhD, UCSF
Stefan Dudli, PhD, University of Zurich
Moderators:
TBA
Roundtable Discussion
Panel and Audience Discussion
Voting/Conclusion
Sunday, February 6, 2022
12:15 PM – 1:50 PM
This portion will be open to Section members only and will include a boxed lunch.
The scientific meeting will have a combined focus on research, networking, and education. Our keynote speaker is an established, industry-based tendon biology investigator. Their presentation will focus on their path to a career in industry, outline the major functions of their job, and will include a Q&A session.
ORS Tendon Research Section Plenary Speaker:
Rebekah Decker, MS, PhD, Novartis Institutes for Biomedical Research
Moderators:
Nat Dyment, PhD, University of Pennsylvania
Alayna Loiselle, PhD, University of Rochester Medical Center
Roundtable Networking Session
This will tie into our networking portion. Networking tables will be focused on industry related topics including industry careers and industry collaborations, as well broad professional development topics.
2:00 PM – 3:00 PM
The research component will be a 3 minute thesis style competition for Section student and post-graduate trainee members selected from accepted abstracts to the ORS 2022 Annual Meeting.
Invited Participants TBA
Moderators:
Nat Dyment, PhD, University of Pennsylvania
Alayna Loiselle, PhD, University of Rochester Medical Center
Research Interest Groups
All are welcome to attend the Virtual Research Interest Group Sessions at a registration rate of $60/each.
Saturday, February 5, 2022
4:30 PM – 6:30 PM
mRNA – A New Class of Drugs for Musculoskeletal Tissue Regeneration?
This RIG will offer an outstanding discussion on the latest advances in mRNA therapeutics and the challenges that this drug may face when applied to musculoskeletal tissue regeneration among three outstanding speakers. Professor Drew Weissman pioneered the discovery of nucleoside modifications to suppress mRNA immunogenicity. His work has revolutionized the field of mRNA therapeutics, and it was instrumental for the development of the COVID-19 vaccine developed by BioNTech/Pfizer and Moderna. Professor Chris Evans has profound experience in the uses of gene therapy as technology platform to solve clinical problems involving bones and joints. He is the lead investigator in an ongoing clinical trial for the administration of sc-rAAV2.5IL-1Ra, a gene therapy carried by a virus, into the knee joint of patients with osteoarthritis. He has been acknowledged as father of musculoskeletal gene therapy. Professor John Cooke has a deep knowledge in fundamental and translational research, with particular emphasis in vascular regeneration. He has developed numerous therapeutic molecules to address various diseases. He is the founder of a Center for RNA Therapeutics that generates mRNA constructs for stem cell and cancer communities. They have experience in the synthesis, purification, validation, and delivery of RNA Therapeutics, for basic and clinical research.
At the end of this session, attendees will have learned about the advantages of mRNA applied to musculoskeletal repair. In particular, progression in fracture healing will be presented. In addition, remaining challenges of mRNA for this application will be presented and discussed. The attendees will have a unique opportunity to discuss these challenges with the keynote speakers. Possible solutions to tackle present challenges will be presented and discussed. Specifically, application of mRNA for protein expression; advantages of mRNA vs. DNA therapeutics; application of mRNA to musculoskeletal repair: State-of-the art and future perspective; needs and challenges in translating mRNA therapeutics to patient care for musculoskeletal repair
Saturday, February 5, 2022
7:00 PM – 9:00 PM
Advance the Science underpinning Foot and Ankle Care by Promoting Communication and Fostering Collaborations
Four specific topics will be addressed during this 2-hour session which include: operative treatment, kinematics/kinetics, diagnosis and imaging, and foot and ankle disorders. Participants in this session can expect to get new insights in foot and ankle biomechanics, diagnoses and treatment, to get a better understanding of normal versus abnormal foot and ankle conditions and related biomechanical and diagnostic measurements, and to assess the research topics that are of interest and/or most relevant.
Sunday, February 6, 2022
3:30 PM – 5:00 PM
Computational Modeling: A Critical and Complementary Tool for Advancing Orthopaedic Research
The objective of this session is to encourage ORS members to seek out new cross-disciplinary collaborations that integrate computational modeling tools into preclinical and clinical studies. Attendees will learn how to identify opportunities to integrate computational model-driven outcome measures into preclinical and clinical studies. The speakers will include practical examples of how models can provide insights not obtainable with other approaches. Speakers will also discuss their approaches to the challenge of developing easily interpretable model outputs. At the conclusion of the session, we will provide participants with a link to a survey asking about their modeling interests (tools and techniques), application areas (alignment with ORS program topics), and interests for future ORS Annual Meeting programming.
Sunday, February 6, 2022
3:30 PM – 5:00 PM
Connecting OA Phenotypes and Treatments: New insights Comparing Joint-Specific OA Pathology
This session will differentiate among OA pathology in the shoulder, hand, hip, and spine and comprehend their relation to knee OA, gain an appreciation for unique mechanical and molecular signatures of joint-specific OA phenotypes, and integrate basic and clinical research perspectives of OA pathologies to develop innovative translational strategies targeted to specific OA phenotypes.
Monday, February 7, 2022
7:00 AM – 9:00 AM
Mechanobiology of Cartilage in the Context of Osteoarthritis and its Role in Regenerative Therapies
This RIG will focus on cartilage mechanobiology and its role in regenerative therapies in the context of osteoarthritis. The RIG will feature renown invited speakers aiming to foster the interchange of knowledge and to discuss new and cutting-edge approaches that help to understand how the mechanical environment contributes to cartilage health and disease at cell and tissue level. At the end of the meeting, there will be time for interactive interdisciplinary discussion, brainstorming and questions.
We expect participants of this RIG will work together and to define pathways to move multi-scale cartilage mechanobiology research forward.
Monday, February 7, 2022
11:15 AM – 12:45 PM
Musculoskeletal Infection: Bridging Science to Clinical Practice
The Musculoskeletal Infection RIG will focus on practical aspects and potential therapy in infection management. In addition to an update of the ongoing consensus workgroup effort, there will be thought‐provoking subsections of the program discussing (1) how to transition in‐vitro biofilm research to in‐vivo testing (keynote), (2) the practical value of the fundamental biofilm formation theory ‘race to the surface’ (debate), (3) clinicians’ view of unmet needs in managing infections, and (4) new frontiers in the fight against infectious organisms including bacteriophage therapy, the potential of mRNA technologies and the use of the microbiome. We aim the program to be both informative and challenging to all levels of ORS attended including students, post‐graduate trainees and faculty.