Coordinated by the ORS Basic Science Education Committee, On the Horizon presents brief articles discussing current scientific investigations that may have future orthopaedic clinical applications.
This feature is presented quarterly in the Journal of the American Academy of Orthopaedic Surgeons (January, April, July, and October).
Please read and enjoy the following articles.
Click the title to read article.
Biophysics Rules the Cell Culture but Has Yet to Reach the Clinic: Why Is That?
Mechanical Signals as Regulators or Cartilage Degeneration and Regeneration
Future Treatment Strategies for Delayed Bone Healing: An Osteoimmunologic Approach
Reverse Dynamization: A Novel Approach to Bone Healing
Role of Subchondral Bone in Articular Cartilage Degeneration and Repair
Using Mathematical Modeling to Design Effective Regenerative Medicine Strategies for Orthopaedics
Emerging Concepts in Gene Therapy for Osteoarthritis
Frontiers in Medical Device Design: An Approach for Making Arthroplasty Affordable Globally
Mesenchymal Stem Cells as a Source of Repair Cytokines: Mesenchymal Stem Cells as the Conductor
Endogenous Cell Homing for Intervertebral Disk Regeneration
Wnt Signaling: An Emerging Target for Bone Regeneration
Biomaterials for Cartilage Regeneration
Optimizing BMP-2-induced bone repair with FGF-2
Mechanical Loading: Potential Preventive and Therapeutic Strategy for Osteoarthritis
Recent Progress in Osteoarthritis Research
Musculoskeletal Modeling for Hip Replacement Outcomes Analyses and Other Applications
Optimizing Stem Cell Engineering for Orthopaedic Applications
Update on Biologics in the Treatment of Rotator Cuff Disease
Serum Biomarkers as Predictors of Stage of Work-related Musculoskeletal Disorders
Using Computational Simulation for Analysis and Development of Next-generation Orthopaedic Devices
How Do Statistical Differences in Matrix-sensitive Magnetic Resonance Outcomes Translate Into Clinical Assignment Rules?
Synovial Stem Cells in Musculoskeletal Regeneration
Annexins: Novel Therapeutics Targets for the Treatment of Osteoarthritis?
Mesenchymal Stromal Cell Transplantation in the Regeneration of Articular Cartilage & Bone Using a Magnetic Cell Delivery System
The Role of Metabolomics in Osteoarthritis Research
Sex Differences in Osteoarthritis of the Knee
The Roles of Osteocyte Signaling in Bone
Endothelial Progenitor Cells: A Novel Cell-based Therapy in Orthopaedic Surgery
Evolving Strategies To Prevent Implant-associated Infections
Osteoarthritis and Metabolic Syndrome
Autophagy: A New Therapeutic Target in Cartilage Injury and Osteoarthritis
Wnt, Osteosarcoma, and Future Therapy
Nanotechnology in Orthopaedics