Coordinated by the ORS Basic Science Education Committee, On the Horizon presents brief articles discussing current scientific investigations that may have future orthopaedic clinical applications.
This feature is presented quarterly in the Journal of the American Academy of Orthopaedic Surgeons (January, April, July, and October).
Please read and enjoy the following articles.
Click the title to read article.
April 2018
Targeting Osteogenesis-Angiogenesis Coupling for Bone Repair
January 2018
Arthritis Gene Therapy Approved in Korea
December 2017
Mysteries Behind the Cellular Content of Tendon Tissues
July 2017
Biophysics Rules the Cell Culture but Has Yet to Reach the Clinic: Why Is That?
April 2017
Mechanical Signals as Regulators or Cartilage Degeneration and Regeneration
January 2017
October 2016
Future Treatment Strategies for Delayed Bone Healing: An Osteoimmunologic Approach
July 2016
Reverse Dynamization: A Novel Approach to Bone Healing
April 2016
Role of Subchondral Bone in Articular Cartilage Degeneration and Repair
January 2016
Using Mathematical Modeling to Design Effective Regenerative Medicine Strategies for Orthopaedics
October 2015
Emerging Concepts in Gene Therapy for Osteoarthritis
Frontiers in Medical Device Design: An Approach for Making Arthroplasty Affordable Globally
July 2015
Mesenchymal Stem Cells as a Source of Repair Cytokines: Mesenchymal Stem Cells as the Conductor
April 2015
Endogenous Cell Homing for Intervertebral Disk Regeneration
January 2015
Wnt Signaling: An Emerging Target for Bone Regeneration
October 2014
Biomaterials for Cartilage Regeneration
Optimizing BMP-2-induced bone repair with FGF-2
July 2014
Mechanical Loading: Potential Preventive and Therapeutic Strategy for Osteoarthritis
Recent Progress in Osteoarthritis Research
April 2014
Musculoskeletal Modeling for Hip Replacement Outcomes Analyses and Other Applications
January 2014
Optimizing Stem Cell Engineering for Orthopaedic Applications
October 2013
Update on Biologics in the Treatment of Rotator Cuff Disease
Serum Biomarkers as Predictors of Stage of Work-related Musculoskeletal Disorders
July 2013
Using Computational Simulation for Analysis and Development of Next-generation Orthopaedic Devices
April 2013
Synovial Stem Cells in Musculoskeletal Regeneration
Annexins: Novel Therapeutics Targets for the Treatment of Osteoarthritis?
January 2013
The Role of Metabolomics in Osteoarthritis Research
October 2012
Sex Differences in Osteoarthritis of the Knee
The Roles of Osteocyte Signaling in Bone
Endothelial Progenitor Cells: A Novel Cell-based Therapy in Orthopaedic Surgery
July 2012
Evolving Strategies To Prevent Implant-associated Infections
April 2012
Osteoarthritis and Metabolic Syndrome
Autophagy: A New Therapeutic Target in Cartilage Injury and Osteoarthritis