The Orthopaedic Research Society (ORS) and the Orland Bethel Family Musculoskeletal Research Center (BMRC) have joined together to offer a fellowship to new-in-career scientists. The BMRC/ORS Fellowship prioritizes support of early career scientists to produce breakthrough treatments for musculoskeletal ailments.

Program Description

The Orland Bethel Family Musculoskeletal Research Center (BMRC) was created in 2024 by the Orland Bethel Family Foundation’s gift, matched by the University of Pittsburgh School of Medicine. The BMRC enables the University of Pittsburgh to elevate its study of musculoskeletal disorders, including bone and muscular diseases, degenerative arthritis, fragility fractures, spinal pathology, cartilage and tendon pathology by attracting and retaining top scientists to advance leading-edge research. The BMRC prioritizes support of early career scientists, both within and outside of the University of Pittsburgh, to produce breakthrough treatments for musculoskeletal ailments.

The goal of the BMRC/ORS Fellowship Program is to support the generation of critical preliminary data for larger grant applications, leading to breakthrough treatments for musculoskeletal disease. Two levels of BMRC/ORS Fellowship support are currently available — $20,000 awards for postdoctoral scholars or medical residents and $30,000 awards for junior faculty members — to support translational basic science and clinical musculoskeletal research.

The BMRC will award between 4-6 BMRC/ORS Fellowships in 2025. All recipients must be active ORS members.

Overview

The ORS and Orland Bethel Family Musculoskeletal Research Center (BMRC) support translational basic science and clinical musculoskeletal research by awarding $20,000 to postdoctoral scholars or medical residents; and $30,000 to junior faculty members.

Eligibility

  • Postdoctoral scholars/residents must have completed a PhD, MD or DO degree within 5 years of the application date (approved institutional leaves of absence excluded).
  • Junior faculty (research assistant professor, assistant professor or equivalent) must be within 5 years of starting their first faculty position (approved institutional leaves of absence excluded).
  • All applicants should also have not received grants totaling more than $75,000/year in direct research
  • Applicants must verify that they have legal work status in the United States and that all research will be performed in laboratories located in the United States.

BMRC is dedicated to improving diversity, equity, inclusion in musculoskeletal research. Investigators who are underrepresented in medicine or STEM fields are encouraged to apply.

Program Details

The BMRC Postdoctoral/Resident Fellowship award is for one year and in the amount of $20,000. The BMRC Junior Faculty Fellowship award is for one year and in the amount of $30,000. All recipients must be active members of the Orthopaedic Research Society. Funding is to support generation of preliminary data for subsequent larger grant applications. Allowable expenses include salary (up to 20% total of award), research supplies, animals, equipment, professional travel or publication fees. No indirect costs are permitted.

All 2025 BMRC fellows will be required to attend and present their work at the BMRC Research Symposium in Pittsburgh, PA in September 2026. Travel to the BMRC Research Symposium is not included with this award and should be included in the proposal budget if necessary.

Application Details

  • April 1, 2025: Letter of Intent (LOI) due
  • May 20, 2025: Notification of selection for full application
  • July 15, 2025: Full grant application is due
  • September 3, 2025: Award Announcement
  • October 1, 2025: Start date of award
  • September 30, 2026: End date of award

Letter of Intent Details

The LOI will be submitted on the ORS website and will require the following combined into one PDF document:

  • Cover page:
    • Title of application
    • Principal investigator name, academic position, institution
    • Co-investigator(s) name, role, institution
  • Description of research project (1 page limit, Arial font size 11pt, ½” margin)
    • Significance, innovation, specific aims, and hypothesis
  • Impact statement (300 word limit)
    • Describe how this project reflects the mission of the
    • Describe how this award will impact your career and lead to preliminary data for larger future funding/research studies.
  • Biosketch –NIH formatted biosketch of the principal investigator only. Do not exceed 5 pages.

Full Grant Application Details

Materials required will include the following combined into one PDF document:

  • Cover page
    • Title of application
    • Principal investigator name, academic position, institution
    • Co-investigator(s) name, role, institution
  • Letter of support from department chair stating that necessary support (resources, salary, protected time) will be provided.
  • Abstract of research project (1 page limit) –Include significance and innovation, specific aims, approach. Describe how this project reflects the mission of the BMRC.
  • Proposal – Maximum of 4 pages (excluding references), Arial font size 11pt, ½” margin
    • Specific aims (One page)
    • Significance, innovation, (preliminary studies, if any), approach, a timeline (Three pages)
    • References (not included in 4-page limit)
    • Budget & budget justification – Allowable expenses include salary (up to 20% total of award), research supplies, animals, equipment, professional travel or publication fees. No indirect costs are Cost sharing is permitted with other funding, but please indicate other support in budget.
  • Biosketches –NIH formatted biosketch of the candidate and key collaborators/ Limit to 5 pages per person.
  • Studies involving human subjects or vertebrate animals must include protection plan as appropriate.

For questions and additional information: Contact Laurie Dearolf, PhD at [email protected].

Congratulations to the following individuals on their selection as the inaugural Bethel Fellows!

Postdoc/Residents and Their Topics:

Kevin Burt, PhD
Postdoctoral Fellow, University of Pennsylvania
Immune Cell Phenotyping During Spine Destabilization

Varun Arvid, MD, PhD
Orthopaedic Surgery Resident, Columbia University
Targeting Myotendinous Elongation for the Treatment of Neuromuscular Contracture

Rebecca Irwin, PhD
Postdoctoral Fellow, Cornell University
Intravital Multi-Photon Imaging of the Meniscus to Reveal Systemic Factors in Injury and Repair

Junior Faculty and Their Topics:

Alice Goodwin, DDS, PhD
Assistant Professor, University of Pittsburgh
SIX6; a New Candidate Gene in the Etiopathogenesis of Pierre Robin Sequence

Natalia Harasymowicz, PhD
Assistant Professor, University of Utah
Elucidation of the Role of T Cells in Obesity-Induced Osteoarthritis