Current Title and Department: Research Lab Manager, Department of Orthopedics

Current Employer: Rhode Island Hospital, Warren Alpert Medical School of Brown University

Undergraduate Degree, University: VIT University, India

Graduate Degree, University: VIT University, India

Mentors: Dr. Chathuraka Jayasuriya, PhD

Could you describe the path you’ve taken in meniscus research? How did it evolve?

My research journey in meniscus repair began with a focus on understanding the regenerative capacity of the meniscus and the factors that limit its natural healing, particularly in the context of injury. Over time, I’ve leveraged using progenitor cells to enhance repair and regeneration. The goal of my work has evolved into developing novel translational strategies to not only improve the structural integrity of the meniscus but also to enhance its function by promoting integrative repair by using different animal models from rats to minipigs. Through this research, we aim to bridge the gap between basic science and clinical applications, developing therapies that can be translated into effective, long-term treatments for patients.

When you started in meniscus research, what was your biggest question? Do you think its answered?

My initial biggest question was how we could repair or regenerate the meniscus effectively, given its limited healing capacity. This is still a huge question in the field, but significant advances have been made in tissue engineering and biologic therapies. While there’s been substantial progress, I wouldn’t say the question is fully answered, as we’re still striving for truly reliable, long-term solutions that work across a wide range of patient profiles.

What collaboration was the most unexpected of your career? How did it impact your work today?

One of the most unexpected collaborations in my career came when I started working with research engineers, particularly using Tekscan technology for gait analysis. Initially, my focus was primarily on tissue repair, but integrating Tekscan’s pressure mapping system to analyze large animal model gait provided invaluable insights into how meniscus repair and regeneration impact joint function. This collaboration allowed us to assess the real-world effects of our therapies, particularly in terms of how they influence movement patterns and load distribution during walking or running. It was a pivotal shift in my approach, emphasizing the importance of not just repairing the tissue but also restoring full functional capacity. This partnership continues to inform and refine my work, helping us develop more comprehensive, patient-centered treatment strategies.”

In your opinion, what is the current open question in the meniscus field right now?

The biggest open question right now is how we can promote complete meniscus regeneration. While we’ve made progress in understanding meniscus repair, achieving full tissue regeneration, especially in the avascular zone, remains elusive. We still don’t have a one-size-fits-all solution for all patients, and there’s a need for better treatments for chronic meniscus injuries.

What advice would you give investigators who are just starting out in the field?

My advice to anyone doing science would be to remain curious and open to new ideas, and don’t be afraid to step outside the traditional boundaries of the field. The meniscus field is evolving rapidly, with advances in biomaterials, regenerative medicine, and biomechanics and thus keeping an interdisciplinary mindset is essential. And lastly, be patient—progress in research is often slow, but persistence pays off.

When you’re not in the lab, what do you like to do for fun?

When I’m not in the lab, I enjoy planning my vacation trips and traveling. Exploring new places helps me unwind and recharge, and I love experiencing different cultures and environments. I also enjoy watching sitcoms—it’s a great way to relax and take my mind off work, especially after a busy day in the lab.

What is the most unusual/unexpected item sitting on your desk right now?

The most unusual item on my desk right now is an empty collagen sponge disc vial from Biomatrix. It’s actually something I need to place an order for, but I keep it on my desk as a reminder to reorder supplies.