The Musculoskeletal Knowledge Portal (MSK-KP) project is a collaboration between the International Federation of Musculoskeletal Research Societies (IFMRS) and scientists and software engineers at the Broad Institute. The IFMRS was conceived in 2012 to provide scientiﬁc opportunities for its member societies with regards to education, collaboration and funding; the IFMRS Big Data Working group is charged with developing a means to share musculoskeletal databases globally.
Exploring the MSK-KP
There are three major entry points to the results in the MSK-KP:
- Enter a gene name, variant ID, or genomic coordinates into the home page search box to view a page with details on genetic associations and epigenomic annotations in that region
- Select a phenotype to view a genome-wide plot and table of the top associations for that phenotype
- Use the Variant Finder tool to retrieve a list of variants meeting custom criteria
Watch the video below for a brief tutorial on navigating the MSK-KP. More written and video documentation will be available on the MSK-KP Resources page.
Video recorded at the ASBMR 2020 Annual Meeting.